{"id":15050,"date":"2016-08-14T19:32:54","date_gmt":"2016-08-14T23:32:54","guid":{"rendered":"http:\/\/www.royzenlab.science\/?page_id=15050"},"modified":"2026-08-13T16:43:33","modified_gmt":"2026-08-13T20:43:33","slug":"publications","status":"publish","type":"page","link":"https:\/\/www.royzenlab.science\/index.php\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_row css_animation=&#8221;&#8221; row_type=&#8221;row&#8221; use_row_as_full_screen_section=&#8221;no&#8221; type=&#8221;full_width&#8221; angled_section=&#8221;no&#8221; text_align=&#8221;left&#8221; background_image_as_pattern=&#8221;without_pattern&#8221;][vc_column][vc_column_text css=&#8221;.vc_custom_1692308894404{padding-top: 85px !important;padding-bottom: 30px !important;}&#8221;]<\/p>\n<h2>BOOK CHAPTERS<\/h2>\n<h2><\/h2>\n<p>[\/vc_column_text][\/vc_column][\/vc_row][vc_row css_animation=&#8221;&#8221; row_type=&#8221;row&#8221; use_row_as_full_screen_section=&#8221;no&#8221; type=&#8221;full_width&#8221; angled_section=&#8221;no&#8221; text_align=&#8221;left&#8221; background_image_as_pattern=&#8221;without_pattern&#8221;][vc_column][vc_separator type=&#8221;normal&#8221; color=&#8221;#000000&#8243;][\/vc_column][\/vc_row][vc_row css_animation=&#8221;&#8221; row_type=&#8221;row&#8221; use_row_as_full_screen_section=&#8221;no&#8221; type=&#8221;full_width&#8221; angled_section=&#8221;no&#8221; text_align=&#8221;left&#8221; background_image_as_pattern=&#8221;without_pattern&#8221;][vc_column][vc_column_text css=&#8221;.vc_custom_1692311003253{padding-bottom: 85px !important;}&#8221;]<strong>2.<\/strong> Handbook of Chemical Biology of Nucleic Acids.\u00a0<em>Springer<\/em>,\u00a0<strong>2023<\/strong>. Vol 1, Part IX, Chapter 80. McClain, I.; Dagci, H.; Royzen, M. Nonchromatographic Purification of Synthetic RNA. DOI: <a href=\"https:\/\/link.springer.com\/referenceworkentry\/10.1007\/978-981-16-1313-5_84-1\" target=\"_blank\" rel=\"noopener\">10.1007\/978-981-16-1313-5_84-1<\/a><\/p>\n<p><strong>1.<\/strong> Handbook of In Vivo Chemistry in Mice: From Lab to Living System.\u00a0<em>Wiley<\/em>,\u00a0<strong>2020<\/strong>. Chapter 9. Royzen, M.; Yee, N.; Mejia Oneto, J. M. In vivo bioconjugation using bio-orthogonal chemistry. ISBN: <a href=\"https:\/\/www.wiley.com\/en-us\/Handbook+of+In+Vivo+Chemistry+in+Mice:+From+Lab+to+Living+System-p-9783527344321\" target=\"_blank\" rel=\"noopener\">978-3-527-34432-1<\/a>[\/vc_column_text][\/vc_column][\/vc_row][vc_row css_animation=&#8221;&#8221; row_type=&#8221;row&#8221; use_row_as_full_screen_section=&#8221;no&#8221; type=&#8221;full_width&#8221; angled_section=&#8221;no&#8221; text_align=&#8221;left&#8221; background_image_as_pattern=&#8221;without_pattern&#8221;][vc_column][vc_separator type=&#8221;normal&#8221; color=&#8221;#000000&#8243;][\/vc_column][\/vc_row][vc_row css_animation=&#8221;&#8221; row_type=&#8221;row&#8221; use_row_as_full_screen_section=&#8221;no&#8221; type=&#8221;full_width&#8221; angled_section=&#8221;no&#8221; text_align=&#8221;left&#8221; background_image_as_pattern=&#8221;without_pattern&#8221;][vc_column][vc_column_text css=&#8221;.vc_custom_1692308996493{padding-top: 85px !important;padding-bottom: 30px !important;}&#8221;]<\/p>\n<h2>JOURNAL ARTICLES<\/h2>\n<h2><\/h2>\n<p>[\/vc_column_text][\/vc_column][\/vc_row][vc_row css_animation=&#8221;&#8221; row_type=&#8221;row&#8221; use_row_as_full_screen_section=&#8221;no&#8221; type=&#8221;full_width&#8221; angled_section=&#8221;no&#8221; text_align=&#8221;left&#8221; background_image_as_pattern=&#8221;without_pattern&#8221;][vc_column][vc_column_text css=&#8221;.vc_custom_1786653806431{padding-bottom: 85px !important;}&#8221;]<strong>31.<\/strong> McClain, I.; Yigit, N. S.; Royzen, M. Non-chromatographic purification of guide RNA for gene-editing experiments.\u00a0<em>Bioorg. Med. Chem. Lett.<\/em>\u00a0<strong>2026<\/strong>,\u00a0<em>140<\/em>, 130740. DOI: <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0960894X26002076\" target=\"_blank\" rel=\"noopener\">10.1016\/j.bmcl.2026.130740<\/a><\/p>\n<p><strong>30.<\/strong> McClain, I.; Pandit, B.; Royzen, M. Coumarin linker facilitates regulation of CRISPR\/Cas9 activity using visible light. <em>RSC Advances<\/em>,\u00a0<strong>2026<\/strong>, in press. DOI: <a href=\"https:\/\/pubs.rsc.org\/ra\/article\/doi\/10.1039\/d6ra04634g\" target=\"_blank\" rel=\"noopener\">10.1039\/d6ra04634g<\/a><\/p>\n<p><strong>29.<\/strong> Pandit, B.; Vangaveti, S.; Sentre, J. F.; McClain, I.; Fuchs, G.; Royzen, M. Bio-orthogonal chemistry-based strategy to Turn-OFF CRISPR-Cas9 activity in solution and live cells. <em>NAR Mol. Med.<\/em>\u00a0<strong>2026<\/strong>,\u00a0<em>3<\/em>, ugag008. DOI: <a href=\"https:\/\/academic.oup.com\/narmolmed\/article\/3\/1\/ugag008\/8445398\" target=\"_blank\" rel=\"noopener\">10.1093\/narmme\/ugag008<\/a><\/p>\n<p><strong>28.<\/strong> Pandit, B.; Hanson, E.; Dagci, H.; Yang, Q.; Yigit, M.; Royzen, M. Effects of N6-methyladenosine (m6A) and 5-methylcytosine (m5C) modifications in the guide region of CRISPR RNA on Cas12a nuclease activity.\u00a0<em>Bioconjugate Chem.<\/em>\u00a0<strong>2025<\/strong>,\u00a0<em>36<\/em>, 2551. DOI: <a href=\"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.bioconjchem.5c00498?ref=PDF\" target=\"_blank\" rel=\"noopener\">10.1021\/acs.bioconjchem.5c00498<\/a><\/p>\n<p><strong>27.<\/strong> McClain, I.; Dagci, H.; Pandit, B.; Royzen, M. Coumarin-based photolabile solid support facilitates nonchromatographic purification of RNA oligonucleotides.\u00a0<em>J. Org. Chem.<\/em>\u00a0<strong>2025<\/strong>,\u00a0<em>90<\/em>, 16326. DOI: <a href=\"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.joc.5c01528?ref=PDF\" target=\"_blank\" rel=\"noopener\">10.1021\/acs.joc.5c01528<\/a><\/p>\n<p><strong>26.<\/strong> Pandit, B.; Fang, L.; Kool, E.; Royzen, M. Reversible RNA acylation using bio-orthogonal chemistry enables temporal control of CRISPR-Cas9 nuclease activity. <em>ACS Chem. Biol.<\/em> <strong>2024<\/strong>. DOI: <span class=\"epub-section__item\"><a class=\"epub-section__doi__text\" href=\"https:\/\/pubs.acs.org\/doi\/10.1021\/acschembio.4c00117\" target=\"_blank\" rel=\"noopener\">10.1021\/acschembio.4c00117<\/a><\/span><\/p>\n<p><strong>25.<\/strong> Hoy, A.; Zheng, Y. Y.; Sheng, J. Royzen, M. Bio-orthogonal chemistry conjugation strategy facilitates investigation of N-methyladenosine and thiouridine guide RNA modifications on CRISPR activity. <em>CRISPR J.<\/em> <strong>2022<\/strong>, <em>5<\/em>, 787. DOI: <span class=\"epub-section__item\"><a class=\"epub-section__doi__text\" href=\"https:\/\/doi.org\/10.1089\/crispr.2022.0065\" target=\"_blank\" rel=\"noopener\">10.1089\/crispr.2022.0065<\/a><\/span><\/p>\n<p><strong>24.<\/strong> Pandit, B.; J. Royzen, M. Recent development of prodrugs of gemcitabine. <em>Genes.<\/em> <strong>2022<\/strong>, <em>13<\/em>, 466. DOI: <a href=\"https:\/\/doi.org\/10.3390\/genes13030466\" target=\"_blank\" rel=\"noopener\">10.3390\/genes13030466<\/a><\/p>\n<p><strong>23.<\/strong> He, M.; Wu, X.; Mao, S.; Haruehanroengra, P.; Khan, I.; Sheng, J. Royzen, M. Non-chromatographic purification of synthetic RNA using bio-orthogonal chemistry. <em>Curr. Protoc.<\/em> <strong>2021<\/strong>, <em>1<\/em>, e247. DOI: <a class=\"epub-doi\" href=\"https:\/\/doi.org\/10.1002\/cpz1.247\" target=\"_blank\" rel=\"noopener\" aria-label=\"Digital Object Identifier\">10.1002\/cpz1.247<\/a><\/p>\n<p><strong>22.<\/strong> Wu, K.; Royzen, M. Chemiluminescent probe for the detection of inverse electron demand Diels-Alder reaction between tetrazine and <em>trans<\/em>-cyclooctene. <em>Bioorg. Med. Chem.<\/em> <strong>2021<\/strong>, <em>47<\/em>, 116400-116406. DOI: <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0968089621004089?via%3Dihub\" target=\"_blank\" rel=\"noopener\">10.1016\/j.bmc.2021.116400<\/a><\/p>\n<p><strong>21.<\/strong> He, M.; Wu, X.; Mao, S; Haruehanroengra, P.; Khan, I.; Sheng, J.; Royzen, M. Bio-orthogonal chemistry enables solid phase synthesis and HPLC &amp; gel-free purification of long RNA oligonucleotides. <em>Chem. Commun. <\/em><strong>2021<\/strong>, <em>57<\/em>, 4263-4266. DOI: <a class=\"text--small\" title=\"Link to landing page via DOI\" href=\"https:\/\/doi.org\/10.1039\/D1CC00096A\" target=\"_blank\" rel=\"noopener\">10.1039\/D1CC00096A<\/a><\/p>\n<p><strong>20.<\/strong> Wu, K.; Yee, N. A.; Srinivasan, S.; Mahmoodi, A.; Zakharian, M.; Mejia Oneto, J. M.; Royzen, M. Click chemistry activated prodrugs against cancer platform to increase the therapeutic potential of chemotherapy through local capture and activation. <em>Chem. Sci. <\/em><strong>2021<\/strong>, <em>12<\/em>, 1259-1271. DOI: <a class=\"text--small\" title=\"Link to landing page via DOI\" href=\"https:\/\/doi.org\/10.1039\/D0SC06099B\" target=\"_blank\" rel=\"noopener\">10.1039\/D0SC06099B<\/a><\/p>\n<p><strong>19.<\/strong> Srinivasan, S.; Yee, N. A.; Wu, K.; Mahmoodi, A.; Royzen, M.; Mejia Oneto, J. M. SQ3370 activates cytotoxic drug via click chemistry at tumor and elicits sustained responses in injected and non-injected lesions. <em>Adv. Ther. <\/em><strong>2021<\/strong>, <em>4<\/em>, 2000243. DOI: <a class=\"epub-doi\" href=\"https:\/\/doi.org\/10.1002\/adtp.202000243\" target=\"_blank\" rel=\"noopener\" aria-label=\"Digital Object Identifier\">10.1002\/adtp.202000243<\/a><\/p>\n<p><strong>18.<\/strong> Czuban, M.; Kulka, M, W.; Wang, L.; Koliszak, A.; Achazi, K.; Schlaich, C.; Donskyi, I. S.; Di Luka, M.; Mejia Oneto, J. M.; Royzen, M.; Haag, R.; , Trampuz, A. Titanium coating with mussel-inspired polymer and bio-orthogonal chemistry enhances antimicrobial activity against <em>S. aureus<\/em>. <em>Mat. Sci. Eng. C, <\/em><strong>2020<\/strong><em>, 116<\/em>, 111109. DOI: <a title=\"DOI URL\" href=\"https:\/\/doi.org\/10.1021\/acscentsci.8b00344\" target=\"_blank\" rel=\"noopener\">10.1021\/acscentsci.8b00344<\/a><\/p>\n<p><strong>17.<\/strong> Wu, X.; Wu, K.; Gaye, F.; Royzen, M. Bond-breaking bio-orthogonal chemistry efficiently uncages fluorescent and therapeutic compounds under physiological conditions. <em>Org. Lett. <\/em><strong>2020<\/strong>, <em>22<\/em>, 6041-6044. DOI: <a title=\"DOI URL\" href=\"https:\/\/doi.org\/10.1021\/acs.orglett.0c02129\" target=\"_blank\" rel=\"noopener\">10.1021\/acs.orglett.0c02129<\/a><\/p>\n<p><strong>16.<\/strong> He, M.; Nadhu, N.; Uyar, B. T.; Royzen, M.; Yigit, M. Small molecule-induced DNA hydrogel with encapsulation and release properties. <em>Chem. Commun. <\/em><strong>2020<\/strong>, <em>56<\/em>, 7313-7316. DOI: <a class=\"text--small\" title=\"Link to landing page via DOI\" href=\"https:\/\/doi.org\/10.1039\/D0CC03439H\" target=\"_blank\" rel=\"noopener\">10.1039\/D0CC03439H<\/a><\/p>\n<p><strong>15.<\/strong> Marcias-Contreras, M.; He, H.; Little, K. N.; Lee, J. P.; Campbell, R. P.; Royzen, M.; Zhu, L. SNAP\/CLIP-Tags and Strain-Promoted Azide-Alkyne Cycloaddition (SPAAC)\/Inverse Electron Demand Diels-Alder (IEDDA) for Intracellular Orthogonal\/Biorthogonal Labeling. <em>Bioconj. Chem. <\/em><strong>2020<\/strong>, <em>31<\/em>, 1370-1381. DOI: <a title=\"DOI URL\" href=\"https:\/\/doi.org\/10.1021\/acs.bioconjchem.0c00107\" target=\"_blank\" rel=\"noopener\">10.1021\/acs.bioconjchem.0c00107<\/a><\/p>\n<p><strong>14.<\/strong> Uyar, T. B.; Wu, K.; He, M.; Khan, I.; Royzen, M.; Yigit, M. Switchable fluorescence of doxorubicin for label-free imaging of bioorthogonal drug release. <em>ChemMedChem, <\/em><strong>2020<\/strong>, <em>15<\/em>, 988-994. DOI: <a class=\"epub-doi\" href=\"https:\/\/doi.org\/10.1002\/cmdc.202000065\" target=\"_blank\" rel=\"noopener\" aria-label=\"Digital Object Identifier\">10.1002\/cmdc.202000065<\/a><\/p>\n<p><strong>13.<\/strong> Kenderdine, T.; Nemati, R.; Baker, A.; Palmer, M.; Ujma, J.; Fitzgibbon, M.; Deng, L.; Royzen, M.; Langridge, J.; Fabris, D. High-Resolution Ion Mobility Spectrometry-Mass Spectrometry of Isomeric\/Isobaric Ribonucleotide Variants. <em>J. Mass Spec. <\/em><strong>2020<\/strong>, <em>55<\/em>, e4465. DOI: <a class=\"epub-doi\" href=\"https:\/\/doi.org\/10.1002\/jms.4465\" target=\"_blank\" rel=\"noopener\" aria-label=\"Digital Object Identifier\">10.1002\/jms.4465<\/a><\/p>\n<p><strong>12.<\/strong> Wu, K.; He, M.; Asare Okai, P. N.; Lin, Q.; Fuchs, G.; Royzen, M. Bio-orthogonal chemistry-based method for fluorescent labelling of ribosomal RNA in live mammalian cells. <em>Chem. Commun. <\/em><strong>2019<\/strong>, <em>55<\/em>, 10456-10459. DOI: <a class=\"text--small\" title=\"Link to landing page via DOI\" href=\"https:\/\/doi.org\/10.1039\/C9CC05346H\" target=\"_blank\" rel=\"noopener\">10.1039\/C9CC05346H<\/a><\/p>\n<p><strong>11.<\/strong> Dai, Y.; Weng, J.; George, J.; Chen, H.; Lin, Q.; Wang, J.; Royzen, M.; Zhang, Q. Three-Component Protein Modification Using Mercaptobenzaldehyde Derivatives. <em>Org. Lett<\/em>. <strong>2019<\/strong>, <em>21<\/em>, 3828-3833. DOI: <a title=\"DOI URL\" href=\"https:\/\/doi.org\/10.1021\/acs.orglett.9b01294\" target=\"_blank\" rel=\"noopener\">10.1021\/acs.orglett.9b01294<\/a><\/p>\n<p><strong>10.<\/strong> Czuban, M.; Srinivasan, S.; Yee, N. A.; Agustin, E.; Koliszak, A.; Miller, E.; Khan, I.; Quinones, I.; Noory, H.; Motola, C.; Volkmer, R.; Di Luca, M.; Trampuz, A.; Royzen, M.; Mejia Oneto, J. M. Bio-orthogonal chemistry and reloadable biomaterial enable local activation of antibiotic prodrugs and enhance treatments against <em>Staphylococcus aureus<\/em> infections. <strong>2018<\/strong>,<em> ACS Cent. Sci.<\/em> <em>4<\/em>, 1624-1632<em>.<\/em> DOI: <a title=\"DOI URL\" href=\"https:\/\/doi.org\/10.1021\/acscentsci.8b00344\" target=\"_blank\" rel=\"noopener\">10.1021\/acscentsci.8b00344<\/a><br \/>\n<strong>9.<\/strong> Khan, I.; Seebald, L. M.; Robertson, N.; Yigit, M. V.; Royzen, M. Controlled in-cell activation of RNA therapeutics using bond-cleaving bio-orthogonal chemistry. <em>Chem. Sci.<\/em> <strong>2017<\/strong>, <em>8<strong>, <\/strong><\/em>5705-5712. DOI: <a class=\"text--small\" title=\"Link to landing page via DOI\" href=\"https:\/\/doi.org\/10.1039\/C7SC01380A\" target=\"_blank\" rel=\"noopener\">10.1039\/C7SC01380A<\/a><\/p>\n<p><strong>8.<\/strong> Robertson, N.; Yang, Y.; Khan, I.; LaMantia, V. E. Royzen, M.; Yigit, M. V. Single-trigger dual-responsive nanoparticles for controllable and sequential prodrug activation. <em>Nanoscale,<\/em> <strong>2017<\/strong>, <em>9<\/em>, 10020-10030. DOI: <a class=\"text--small\" title=\"Link to landing page via DOI\" href=\"https:\/\/doi.org\/10.1039\/C7NR04138A\" target=\"_blank\" rel=\"noopener\">10.1039\/C7NR04138A<\/a><\/p>\n<p><strong>7.<\/strong> Seebald, L. M.; DeMott, C. M.; Ranganathan, S.; Asare Okai, P. N.; Glazunova, A.; Chen, A.; Shekhtman, A.; Royzen, M. Cu(II)-Based Paramagnetic Probe to Study RNA-Protein Interactions by NMR. <em>Inorg. Chem.<\/em> <strong>2017<\/strong>, <em>56<\/em>, 3773-3780. DOI: <a title=\"DOI URL\" href=\"https:\/\/doi.org\/10.1021\/acs.inorgchem.6b02286\" target=\"_blank\" rel=\"noopener\">10.1021\/acs.inorgchem.6b02286<\/a><\/p>\n<p><strong>6.<\/strong> Seebald, L. M.; DeMott, C. M.; Ranganathan, S.; Asare Okai, P. N.; Glazunova, A.; Chen, A.; Shekhtman, A.; Royzen, M. Cobalt-based paramagnetic probe to study RNA-protein interactions by NMR. <em>J. Inorg. Biochem.<\/em> <strong>2017<\/strong>, <em>170<\/em>, 202-208. DOI: <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0162013416303713?via%3Dihub\" target=\"_blank\" rel=\"noopener\">10.1016\/j.jinorgbio.2017.02.024<\/a><\/p>\n<p><strong>5.<\/strong> Steiger, A. K.; Yang, Y.; Royzen, M.; Pluth, M. D. Bio-orthogonal \u201cClick and Release\u201d donation of caged carbonyl sulfide (COS) and hydrogen sulfide (H<sub>2<\/sub>S). <em>Chem. Commun.<\/em> <strong>2017<\/strong>, <em>53<\/em>, 1378-1380. DOI: <a class=\"text--small\" title=\"Link to landing page via DOI\" href=\"https:\/\/doi.org\/10.1039\/C6CC09547J\" target=\"_blank\" rel=\"noopener\">10.1039\/C6CC09547J<\/a><\/p>\n<p><strong>4.<\/strong> Mejia Oneto, J. M.; Khan, I.; Seebald, L.; Royzen, M. In vivo bioorthogonal chemistry enables local hydrogel and systemic pro-drug to treat soft tissue sarcoma. <em>ACS Cent. Sci. <\/em><strong>2016<\/strong>, <em>2<\/em>, 476-482. DOI: <a title=\"DOI URL\" href=\"https:\/\/doi.org\/10.1021\/acscentsci.6b00150\" target=\"_blank\" rel=\"noopener\">10.1021\/acscentsci.6b00150<\/a><\/p>\n<p><strong>3.<\/strong> Khan, I.; Agris, P. F.; Yigit, Y. V.; Royzen, M. In situ activation of a doxorubicin prodrug using imaging-capable nanoparticles. <em>Chem. Commun.<\/em> <strong>2016<\/strong>, <em>52<\/em>, 6174-6177. DOI: <a class=\"text--small\" title=\"Link to landing page via DOI\" href=\"https:\/\/doi.org\/10.1039\/C6CC01024E\" target=\"_blank\" rel=\"noopener\">10.1039\/C6CC01024E<\/a><\/p>\n<p><strong>2.<\/strong> Agustin, E.; Asare-Okai, P. N.; Khan, I.; Miller, M. R.; Wang, R.; Sheng, J.; Royzen, M. Fast click-slow release strategy towards solid phase synthesis of RNA. <em>Chem. Commun<\/em>. <strong>2016<\/strong>, <em>52<\/em>, 1405-1408. DOI: <a class=\"text--small\" title=\"Link to landing page via DOI\" href=\"https:\/\/doi.org\/10.1039\/C5CC05392G\" target=\"_blank\" rel=\"noopener\">10.1039\/C5CC05392G<\/a><\/p>\n<p><strong>1.<\/strong> Asare-Okai, P. N.; Agustin, E.; Fabris, D.; Royzen, M. Site-specific fluorescence labeling of RNA using bio-orthogonal reaction of <em>trans<\/em>-cyclooctene and tetrazine. <em>Chem. Commun.<\/em> <strong>2014<\/strong>, <em>50<\/em>, 7844-7847. DOI: <a class=\"text--small\" title=\"Link to landing page via DOI\" href=\"https:\/\/doi.org\/10.1039\/C4CC02435D\" target=\"_blank\" rel=\"noopener\">10.1039\/C4CC02435D<\/a>[\/vc_column_text][\/vc_column][\/vc_row][vc_row css_animation=&#8221;&#8221; row_type=&#8221;row&#8221; use_row_as_full_screen_section=&#8221;no&#8221; type=&#8221;full_width&#8221; angled_section=&#8221;no&#8221; text_align=&#8221;left&#8221; background_image_as_pattern=&#8221;without_pattern&#8221;][vc_column][vc_column_text css=&#8221;.vc_custom_1680532663589{padding-top: 40px !important;padding-bottom: 20px !important;}&#8221;]<\/p>\n<h2>PUBLICATIONS PRIOR TO UNIVERSITY AT ALBANY<\/h2>\n<p>[\/vc_column_text][\/vc_column][\/vc_row][vc_row css_animation=&#8221;&#8221; row_type=&#8221;row&#8221; use_row_as_full_screen_section=&#8221;no&#8221; type=&#8221;full_width&#8221; angled_section=&#8221;no&#8221; text_align=&#8221;left&#8221; background_image_as_pattern=&#8221;without_pattern&#8221;][vc_column][vc_column_text css=&#8221;.vc_custom_1691331808100{padding-bottom: 85px !important;}&#8221;]<strong>14.<\/strong> Song, Y.; Suntharalingam, K.; Yeung, J.; Royzen, M.; Lippard, S. J. Synthesis and characterization of Pt(IV) fluorescein conjugates to investigate Pt(IV) intracellular transformations. <em>Bioconj. Chem. <\/em><strong>2013<\/strong>, <em>24<\/em>, 1733-1740.<\/p>\n<p><strong>13.<\/strong> Royzen, M.; Canary, J.W.\u00a0 Structural parameters in 8-hydroxyquinoline tripodal ligand complexes in zinc(II) affect fluorescence quantum yield,\u201d <em>Polyhedron<\/em>, <strong>2012<\/strong>, <em>58<\/em>, 85-91.<\/p>\n<p><strong>12.<\/strong> Royzen, M.; Wilson, J. J.; Lippard, S. J. Physical and structural properties of [Cu(BOT1)Cl]Cl, a fluorescent imaging probe for HNO. <em>J. Inorg. Biochem.<\/em> <strong>2013<\/strong>, <em>118<\/em>, 162-170.<\/p>\n<p><strong>11.<\/strong> Xu, F.; Chung, J. Y. L.; Moore, J. C.; Liu, Z.; Yoshikawa, N.; Hoerrner, R. S.; Lee, J.; Royzen, M.; Cleator, E.; Gibson, A. G.; Dunn, R.; Maloney, K. M.; Alam, M.; Goodyear, A.; Lynch, J.; Yasuda, N.; Devine, P. N. Asymmetric synthesis of cis-2,5-disubstituted pyrrolidine, the core scaffold of beta-AR agonists. <em>J. Org. Lett.<\/em> <strong>2013<\/strong>, <em>15<\/em>, 1342-1345.<\/p>\n<p><strong>10.<\/strong> Filipovic, M. R.; Miljkovic, J. L.; Nauser, T.; Royzen, M.; Klos, K.; Shubina, T.; Koppenol, W. H.; Lippard, S. J.; Ivanovi\u0107-Burmazovi\u0107, I. <em>J. Am. Chem. Soc.<\/em> <strong>2012<\/strong>, <em>134<\/em>, 12016-12027.<br \/>\nA Science and Technology, News of The Week describing this work appeared in <em>Chemical and Engineering News<\/em> <strong>2012<\/strong>, <em>80<\/em> (28), 5.<\/p>\n<p><strong>9.<\/strong> Gruppi, F.; Liang, J.; Bartelle, B. B.; Royzen, M.; Turnbull, D. H.; Canary, J. Supramolecular metal displacement allows on-fluorescence analysis of manganese(II) in living cells. <em>Chem. Commun.<\/em> <strong>2012<\/strong>, <em>48<\/em>, 10778-10780.<\/p>\n<p><strong>8.<\/strong> Royzen, M.; Taylor, M. T.; DeAngelis, A.; Fox, J. M. Total synthesis of hyacinthacine A2: stereocontrolled 5-aza-cyclooctene photoisomerization and transannular hydroamination with planar-to-point chirality transfer. <em>Chem. Sci.<\/em> <strong>2011<\/strong>, <em>2<\/em>, 2162-2165.<\/p>\n<p><strong>7.<\/strong> Blackman, M. L.; Royzen, M.; Fox, J. M. Tetrazine ligation: fast bioconjugation based on inverse-electron-demand Diels-Alder reactivity. <em>J. Am. Chem. So<\/em>. <strong>2008<\/strong>, <em>130<\/em>, 13518-13519.<br \/>\nA Science and Technology Concentrate describing this work appeared in <em>Chemical and Engineering News<\/em> <strong>2008<\/strong>, <em>86<\/em> (40), 8.<\/p>\n<p><strong>6.<\/strong> Royzen, M.; Yap, G. P. A.; Fox, J. M. A photochemical synthesis of functionalized trans-cyclooctenes driven by metal complexation. <em>J. Am. Chem. Soc<\/em>. <strong>2008<\/strong>, <em>130<\/em>, 3760-3761.<\/p>\n<p><strong>5.<\/strong> Royzen, M.; Durandin, A.; Young, V. G.; Geacintov, N. E.; Canary, J. W. A sensitive probe for the detection of Zn(II) by time-resolved fluorescence. <em>J. Am. Chem. Soc<\/em>. <strong>2006<\/strong>, <em>128<\/em>, 3854-3855.<\/p>\n<p><strong>4.<\/strong> Royzen, M.; Dai, Z.; Canary, J. W. Ratiometric displacement approach to Cu(II) sensing by fluorescence. <em>J. Am. Chem. Soc<\/em>. <strong>2005<\/strong>, <em>127<\/em>, 1612-1613.<\/p>\n<p><strong>3.<\/strong> Choe, Y. H.; Conover, C. D.; Wu, D.; Royzen, M.; Greenwald, R. B. Anticancer drug delivery systems: N-acyl poly(ethylene glycol) prodrugs of ara-C. Efficacy in solid tumors. <em>J. Control Release<\/em>. <strong>2002<\/strong>, <em>79<\/em>, 41-53.<\/p>\n<p><strong>2.<\/strong> Choe, Y. H.; Conover, C. D.; Wu, D.; Royzen, M.; Gervacio, Y.; Borowski, V.; Mehlig, M. Anticancer drug delivery systems: N-acyl poly(ethylene glycol) prodrugs of ara-C: II. Efficacy in ascites and solid tumors. <em>J. Control Release<\/em>. <strong>2002<\/strong>, <em>79<\/em>, 55-70.<\/p>\n<p><strong>1.<\/strong> Greenwald, R. B.; Choe, Y. H.; Conover, C. D.; Shum, K.; Wu, D.; Royzen, M. Drug delivery systems based on trimethyl lock lactonization: poly(ethylene glycol) prodrugs of amino-containing compounds. <em>J. Med. Chem.\u00a0<\/em> <strong>2000<\/strong>, <em>43<\/em>, 475-487.[\/vc_column_text][\/vc_column][\/vc_row][vc_row css_animation=&#8221;&#8221; row_type=&#8221;row&#8221; use_row_as_full_screen_section=&#8221;no&#8221; type=&#8221;full_width&#8221; angled_section=&#8221;no&#8221; text_align=&#8221;left&#8221; background_image_as_pattern=&#8221;without_pattern&#8221;][vc_column][vc_empty_space][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>[vc_row css_animation=&#8221;&#8221; row_type=&#8221;row&#8221; use_row_as_full_screen_section=&#8221;no&#8221; type=&#8221;full_width&#8221; angled_section=&#8221;no&#8221; text_align=&#8221;left&#8221; background_image_as_pattern=&#8221;without_pattern&#8221;][vc_column][vc_column_text css=&#8221;.vc_custom_1692308894404{padding-top: 85px !important;padding-bottom: 30px !important;}&#8221;] BOOK CHAPTERS [\/vc_column_text][\/vc_column][\/vc_row][vc_row css_animation=&#8221;&#8221; row_type=&#8221;row&#8221; use_row_as_full_screen_section=&#8221;no&#8221; type=&#8221;full_width&#8221; angled_section=&#8221;no&#8221; text_align=&#8221;left&#8221; background_image_as_pattern=&#8221;without_pattern&#8221;][vc_column][vc_separator type=&#8221;normal&#8221; color=&#8221;#000000&#8243;][\/vc_column][\/vc_row][vc_row css_animation=&#8221;&#8221; row_type=&#8221;row&#8221; use_row_as_full_screen_section=&#8221;no&#8221; type=&#8221;full_width&#8221; angled_section=&#8221;no&#8221; text_align=&#8221;left&#8221; background_image_as_pattern=&#8221;without_pattern&#8221;][vc_column][vc_column_text css=&#8221;.vc_custom_1692311003253{padding-bottom: 85px !important;}&#8221;]2. Handbook of Chemical Biology of Nucleic Acids.\u00a0Springer,\u00a02023. Vol 1, Part&#8230;<\/p>\n","protected":false},"author":4,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-15050","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/www.royzenlab.science\/index.php\/wp-json\/wp\/v2\/pages\/15050","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.royzenlab.science\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.royzenlab.science\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.royzenlab.science\/index.php\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/www.royzenlab.science\/index.php\/wp-json\/wp\/v2\/comments?post=15050"}],"version-history":[{"count":145,"href":"https:\/\/www.royzenlab.science\/index.php\/wp-json\/wp\/v2\/pages\/15050\/revisions"}],"predecessor-version":[{"id":15845,"href":"https:\/\/www.royzenlab.science\/index.php\/wp-json\/wp\/v2\/pages\/15050\/revisions\/15845"}],"wp:attachment":[{"href":"https:\/\/www.royzenlab.science\/index.php\/wp-json\/wp\/v2\/media?parent=15050"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}